Anti-inflammatory property of Atalantia retusa Merr. (Rutaceae) non-polar extraction on rats
Date of Publication
2009
Document Type
Bachelor's Thesis
Degree Name
Bachelor of Science in Biology
College
College of Science
Department/Unit
Biology
Thesis Adviser
Ramos, Gliceria
Abstract/Summary
The continuous search for bioactive compounds capable of effectively inhibiting inflammation has directed the study to investigate on the anti-inflammatory potential of the non-polar extract of Atalantia retusa Merr. leaves using rats as model animals. The anti-inflammatory property of the leaf hexane extract was investigated using carrageenan-induced rat paw edema on male Sprague-Dawley rats. The degree of swelling was significantly (P<0.05) reduced by the administration of 1.43 mg/Kg BW starting at 1.0h to 3.0h after carrageenan injection which is comparable with Diclofenac (Sodium Difenax) suggesting the central and peripheral actions of the extract. The current study demonstrated the high impact potential of A. retusa as anti-inflammatory drug.
Abstract Format
html
Format
Electronic
Accession Number
CDTU019092
Shelf Location
Archives, The Learning Commons, 12F Henry Sy Sr. Hall
Physical Description
1 computer optical disc ; 4 3/4 in.
Recommended Citation
Cueto, J. (2009). Anti-inflammatory property of Atalantia retusa Merr. (Rutaceae) non-polar extraction on rats. Retrieved from https://animorepository.dlsu.edu.ph/etd_bachelors/2483
