Chemical constituents of Ficus odorata

College

College of Science

Department/Unit

Chemistry

Document Type

Article

Source Title

Pharmaceutical Chemistry Journal

Volume

46

Issue

4

First Page

225

Last Page

227

Publication Date

7-1-2012

Abstract

A dichloromethane extract of the leaves of Ficus odorata (Moreaceae family) contains ′-sitosteryl- 3β-glucopyranoside-6′-O-palmitate (1), squalene (2), lutein (3), α;-amyrin acetate (4), lupeol acetate (5), and β-carotene (6). The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy. Compound 1 was tested for cytotoxicity using sulforhodamine B assay against the human lung adenocarcinoma epithelial cell line (A549), human stomach adenocarcinoma cell line (AGS), human colon adenocarcinoma (HT29) and human prostate cancer cell line (PC3). It exhibited cytotoxicity against AGS cell line with 60.28% growth inhibition. © 2012 Springer Science+Business Media, Inc.

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Digitial Object Identifier (DOI)

10.1007/s11094-012-0767-3

Disciplines

Chemistry

Keywords

Ficus (Plants)--Analysis; Moraceae--Analysis

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