New triterpenes from Barringtonia asiatica

College

College of Science

Department/Unit

Chemistry

Document Type

Article

Source Title

Chemical and Pharmaceutical Bulletin

Volume

59

Issue

6

First Page

778

Last Page

782

Publication Date

6-6-2011

Abstract

The leaves of Barringtonia asiatica afforded two new triterpenes, germanicol caffeoyl ester (1) and camelliagenone (2). Their structures were elucidated by extensive 1D- and 2D-NMR spectroscopy. It also afforded germanicol trans-coumaroyl ester (3), germanicol cis-coumaroyl ester (4), germanicol (5), camelliagenin A (6), spinasterol, sitosterol, squalene, lutein and trilinolein. Compounds 3, spinasterol and trilinolein were isolated from the fruits, while the seeds yielded spinasterol, squalene, linoleic acid and trilinolein. Compounds 1-5 exhibited antifungal activity against Candida albicans, 1-3 and 5 showed antibacterial activity against Staphylococcus aureus, while 5 is active against Pseudomonas aeruginosa. © 2011 Pharmaceutical Society of Japan.

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Digitial Object Identifier (DOI)

10.1248/cpb.59.778

Disciplines

Chemistry

Keywords

Lecythidaceae--Analysis; Anti-infective agents

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