An antifungal cadinanolide from Pseudoelephantopus spicatus

College

College of Science

Department/Unit

Chemistry

Document Type

Article

Source Title

Chemical and Pharmaceutical Bulletin

Volume

49

Issue

10

First Page

1359

Last Page

1361

Publication Date

11-17-2001

Abstract

A new sesquiterpene lactone was obtained from the chloroform extract of Pseudoelephantopus spicatus. Its structure was elucidated by extensive one dimentional (1D) and 2D NMR spectroscopy and mass spectrometry. It was found to exhibit moderate antifungal activity against C. albicans and A. niger, and low activity against T. mentagrophytes, S. aureus, E. coli and P. aeruginosa. It was inactive against B. subtilis.

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Digitial Object Identifier (DOI)

10.1248/cpb.49.1359

Disciplines

Chemistry

Keywords

Compositae--Analysis; Antifungal agents

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