Diastereomeric diterpenes from Coleus blumei

College

College of Science

Department/Unit

Chemistry

Document Type

Article

Source Title

Chemical and Pharmaceutical Bulletin

Volume

49

Issue

7

First Page

927

Last Page

929

Publication Date

7-20-2001

Abstract

The chloroform extract of the air-dried leaves of Coleus blumei afforded a mixture of diastereomers of a new abietane type diterpene whose structures were elucidated by extensive one and two dimensional (1D, 2D) NMR and mass spectrometry. Acetylation of the mixture afforded a single compound. Antimicrobial tests on the diterpene indicate that it is active against Bacillus subtilis, Pseudomonas aeruginosa and Candida albicans.

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Digitial Object Identifier (DOI)

10.1248/cpb.49.927

Disciplines

Chemistry

Keywords

Coleus--Analysis

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