Angio-suppressive triterpenoids from Ardisia cf. elliptica (subgenus Tinus) on duck (Anas platyrynchosL.) chorioallantoic membrane
College
College of Science
Department/Unit
Chemistry
Document Type
Article
Source Title
Chinese Journal of Natural Medicines
Volume
11
Issue
2
First Page
128
Last Page
138
Publication Date
1-1-2013
Abstract
The dichloromethane extract of the air-dried leaves of Ardisia cf. elliptica (subgenus Tinus) afforded a mixture of bauerenol (1a), α-amyrin (1b) and β-amyrin (1c). Their structures were identified by NMR spectroscopy. Mixtures of the triterpenes (1a-1c) at ratios of 2:2:1, 2:2:3 and 1:1:1 were tested for their angio-suppressive effects on duck chorioallantoic membrane (CAM). All three ratios were found to be effective in restricting inter-capillary length, while 1a-1c (2:2:1) was most effective in reducing branch point density with 100% CAM viability and embryo survivability, suggesting a high impact angio-suppressive potential of 1a-1c (2:2:1). © 2013 China Pharmaceutical University.
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Digitial Object Identifier (DOI)
10.1016/S1875-5364(13)60039-4
Recommended Citation
Raga, D. D., Herrera, A. A., & Ragasa, C. Y. (2013). Angio-suppressive triterpenoids from Ardisia cf. elliptica (subgenus Tinus) on duck (Anas platyrynchosL.) chorioallantoic membrane. Chinese Journal of Natural Medicines, 11 (2), 128-138. https://doi.org/10.1016/S1875-5364(13)60039-4
Disciplines
Chemistry
Keywords
Primulaceae--Analysis
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