Chemical constituents of Aglaia loheri

Authors

Consolacion Y. Ragasa, De La Salle University, Manila
Oscar B. Torres, De La Salle University, Manila
Chien Chang Shen, De La Salle University, Manila
Michelle Gayle R. Mejia, National Research Institute of Chinese Medicine Taiwan
Regina Joyce Ferrer, National Research Institute of Chinese Medicine Taiwan
Sonia D. Jacinto, National Research Institute of Chinese Medicine Taiwan

College

College of Science

Department/Unit

Chemistry

Document Type

Article

Source Title

Pharmacognosy Journal

Volume

4

Issue

32

First Page

29

Last Page

31

Publication Date

11-1-2012

Abstract

The dichloromethane extract of the leaves of Aglaia loheri afforded spinasterol (1), trilinolein (2) and phytyl fatty acid ester (3). The structures of 1-2 were identified by comparison of their 13C NMR data with those reported in the literature. Compounds 1, 2 and 3 were evaluated for cytotoxicity against the colon carcinoma (HCT 116) using the MTT assay. They exhibited moderate cytotoxicity against HCT 116 with IC50 values of 40.52, 46.73 and 40.06, respectively. © 2012 Pharmacognosy Network Worldwide [Phcog.Net].

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Digitial Object Identifier (DOI)

10.5530/pj.2012.32.6

Recommended Citation

Ragasa, C. Y., Torres, O. B., Shen, C., Mejia, M. R., Ferrer, R., & Jacinto, S. D. (2012). Chemical constituents of Aglaia loheri. Pharmacognosy Journal, 4 (32), 29-31. https://doi.org/10.5530/pj.2012.32.6

Disciplines

Chemistry

Keywords

Meliaceae--Analysis

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