Date of Publication

2-23-2022

Document Type

Dissertation/Thesis

Degree Name

Bachelor of Science in Biology major in Medical Biology

Subject Categories

Biology | Plants

College

College of Science

Department/Unit

Biology

Thesis Advisor

Maria Luisa D. Enriquez

Defense Panel Chair

Zeba F. Alam

Defense Panel Member

Mariquit M. De Los Reyes
Mark Christian Felipe R. Redillas

Abstract/Summary

In the Philippines, there is currently an aggressive interest in pursuing studies on medicinal plants in an attempt to discover novel cost-effective and safe cure for human diseases. The main objective of this paper is to come up with a narrative synthesis on the medicinal plants found in Luzon covering a 25-year period (1996-2020). A total of 138 articles published online was used in this study. Data gathered from each article were encoded in a spreadsheet under 5 categories: Journal information, plant demographics, methodology, secondary metabolites, and plant bioactivity. Results showed that of the 138 published papers, 9 were ethnobotanical and 129 were experimental studies. A total of 672 plant species were documented, 464 plants species were from ethnobotanical data and 208 plant species were from experimental data. Most published articles were authored by researchers from NCR, Bicol region, and Central Luzon. Most number of plant species reported were from the CAR. The highest number of medicinal plants reported belong to the family Asteraceae. All experimental publications (n=129) included methods on extract preparation, phytochemical screening, pure compounds identification, and biological activity screening. The plant extracts were mostly prepared from the leaves. The most abundant secondary metabolites obtained were terpenoids, sterols, and flavonoids. The most number of biological activities were exhibited by families Fabaceae and Myrtaceae. Biological activities mostly reported are antimicrobial, anti-cancer, anti-inflammatory, and anti-diabetes. These biological activities were attributed to the presence of secondary metabolites such as alkaloids, terpenoids, sterols, and flavonoids. One hundred twelve plant species were tested for potential cytotoxic activity while 23 were assayed for their genotoxicity. Six secondary metabolites (sterols, flavonoids, tannins, terpenoids, glycosides, and alkaloids) commonly found in medicinal plants exhibited antimicrobial, anti-inflammatory, anti-diabetes, anti-cancer, and heart disease treatment properties. It is recommended that the future narrative synthesis should include published experimental works that are not available online as well as unpublished works from different academic institutions.

Abstract Format

html

Language

English

Format

Electronic

Physical Description

vii, 80 leaves

Keywords

Medicinal plants--Philippines--Luzon; Electronic publications

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Embargo Period

2-23-2022

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