Isolation and characterization of the secondary metabolites: Antidesma ghaesembilla gaertn

Date of Publication

2017

Document Type

Master's Thesis

Degree Name

Master of Science in Chemistry

College

College of Science

Department/Unit

Chemistry

Thesis Adviser

Consolacion Y. Ragasa

Defense Panel Member

Jaime Raul O. Janairo
Glenn V. Alea

Abstract/Summary

Antidesma ghaesembilla, also known as arocep in Ilokano or binayuyu in Tagalog, is a small deciduous tree found in mountainous area of Central and Northern Luzon. The fruits are edible and have a resemblance to blackcurrant. The leaves and bark are utilized as herbal medicines for fever, cough and rheumatism.

Chemical investigation of the dichloromethane extracts of Antidesma ghaesembilla Gaertn. afforded b-friedelinol (AG21L), lupeol (AG13L), squalene (AG9LA), polyprenol (AG12L), b-sitosterol (AG19L) and long-chain hydrocarbons (AG2L) from the leaves; and b-sitosterol (AGF2B) and triacylglycerols (AGF1) from the fruit. The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy, while those of 2-7 were identified by comparison of their NMR data with literature data. This is the first report on the isolation of these compounds from A. ghaesembilla.

Abstract Format

html

Language

English

Format

Electronic

Accession Number

CDTG007152

Shelf Location

Archives, The Learning Commons, 12F Henry Sy Sr. Hall

Physical Description

xii, 108 leaves ; illustrations ; 28 cm. ; +2 computer disc

Keywords

Medicinal plants--Philippines

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