Date of Publication

4-1998

Document Type

Master's Thesis

Degree Name

Master of Science in Chemistry

Subject Categories

Chemistry

College

College of Science

Department/Unit

Chemistry

Thesis Adviser

Consolacion Y. Ragasa

Defense Panel Chair

Gerardo C. Janairo

Defense Panel Member

Jaime Raul O. Janairo
Marissa G. Noel

Abstract/Summary

The chloroform extract of the air-dried leaves of Peperomia pellucida (Linn.) H.B.K. afforded dill-apiol (PP1), pachypophyllin (PP5) and aurantiamide acetate (PP6). The structures of the compounds PP1 and PP5 were elucidated by extensive 1D and 2D NMR Spectroscopy and Mass Spectrometry for compound PP5, while the structure of compoung PP6 was identified by comparison of its 1H NMR spectral data with those reported in the literature of aurantiamide acetate.The antimicrobial analysis conducted for dill-apiol and pachypophyllin using the agar cup method indicate that the two isolates are active against the fungus Trychophyton mentagrophytes with activity indexes (AI) of 0.4 and 2.6 at 40 ug, respectively. However, the two isolates are inactive against the organisms Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeroginosa, Candida albicans and Aspergilus niger. Aurantiamide acetate was not analyzed for its biological activity due to the limited amount of the isolate.

Abstract Format

html

Language

English

Format

Electronic

Accession Number

TG02741

Shelf Location

Archives, The Learning Commons, 12F Henry Sy Sr. Hall

Physical Description

xiv, 147 leaves

Keywords

Aromatic compounds; Chloroform; Extracts; Medicinal plants; Plants--Composition; Microbial sensitivity tests

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