Isolation, characterization and antimicrobial assay of some compounds from Sarcophyton tortuosum
Date of Publication
1991
Document Type
Master's Thesis
Degree Name
Master of Science in Chemistry
Subject Categories
Chemistry
College
College of Science
Department/Unit
Chemistry
Thesis Adviser
Gerardo C. Janairo
Defense Panel Chair
Anamy Paano
Defense Panel Member
Consolacion Ragasa
Elizabeth Ong
Abstract/Summary
The chloroform extract of the marine soft coral Sarcophyton tortuosom was found to contain two compounds with potent antimicrobial properties. The structures of the two compounds were partially elucidated. Based on the spectral evidences (IR, 1H NMR, 13C NMR) and comparison of its 13C chemical shifts with those of sitosterol the structure of ST7/2 was proposed as a steroid, possessing a 3 Beta-hydroxy-delta5 steroid nucleus. The structure of its side chain could not be determined. Analysis of the spectral data of ST4/4 suggested that it was a triglyceride with a cyclopropene ring in the side chain. Both compounds inhibited the growth of all seven test organisms but exhibited their highest inhibitory effect on Bacillus subtilis.
Abstract Format
html
Language
English
Format
Accession Number
TG01969
Shelf Location
Archives, The Learning Commons, 12F Henry Sy Sr. Hall
Physical Description
103 leaves; 28 cm.
Keywords
Corals; Microbiological assay; Microbial sensitivity tests
Recommended Citation
Penalosa, B. A. (1991). Isolation, characterization and antimicrobial assay of some compounds from Sarcophyton tortuosum. Retrieved from https://animorepository.dlsu.edu.ph/etd_masteral/1374
