Effects of Liveraide (Silybum marainum) on the histology of mice (Mus musculus) liver and kidney
Date of Publication
2008
Document Type
Bachelor's Thesis
Degree Name
Bachelor of Science in Biology
Subject Categories
Biology
College
College of Science
Department/Unit
Biology
Thesis Adviser
Michael Ples
Defense Panel Chair
Josefina De Jesus
Abstract/Summary
The study was done to determine the histological effects of varying dose of Liveraide (Silybum marianum), a medicinal herb on the kidneys and livers of laboratory mice (Mus muculus). Twenty four mice were used in the study. The mice were divided into 2 groups and forcefully fed with two different dosages of Liveraide. The first group was given 0.05 mg/ml Liveraide solution once a day, the minimum dosage group. The second group was given 0.11 mg/ml Liveraide solution once a day. The amount of dosage was based from the instruction of the drug use. The laboratory mice had there meals at 7:00am, 1200 noon and 5:00pm. At the first week, the mice were given time to acclimatize and therefore were not given the dosages. At the end of the first week, 2 mice were sacrificed as the control group. For the succeeding 4 weeks, 2 mice were randomly sacrificed. The livers and kidneys were procured and processed. Light microscopy work was done to ascertain the histological conditions of the mice.
Abstract Format
html
Language
English
Format
Electronic
Accession Number
CDTU013896
Shelf Location
Archives, The Learning Commons, 12F, Henry Sy Sr. Hall
Physical Description
1 computer disc ; 4 3/4 in.
Keywords
Milk thistle--Physiological effect; Mice--Histology
Recommended Citation
Pozon, R. G., & Teo, G. (2008). Effects of Liveraide (Silybum marainum) on the histology of mice (Mus musculus) liver and kidney. Retrieved from https://animorepository.dlsu.edu.ph/etd_bachelors/4861
Embargo Period
3-16-2021