Potencial anticancer drug from local virca rosea

Date of Publication

1982

Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Biology

Subject Categories

Biology

College

College of Science

Department/Unit

Biology

Abstract/Summary

Biological assay for anticancer activity of the partially purified isolates of local Vinca rosea Linn showed positive inhibitory activity against Ehrlich Ascites Tumor Cells (EATC). Fractionation of the active constituent which maybe present in the plant was modified from the methodology of Svoboda (Lilly 1979) and four alkaloids were found to be present. Partial purification of the active alkaloidal fraction using thin layer chromatographic procedures was conducted with on of the four alkaloids of the experimental plant, vincaleucoblastine and under the ultraviolet light showed similar color effect as that of the reference alkaloid, vinblastine.

Abstract Format

html

Language

English

Format

Print

Accession Number

TU03093

Shelf Location

Archives, The Learning Commons, 12F, Henry Sy Sr. Hall

Physical Description

53 leaves

Keywords

Virca rosea (Tsisirika); Anticancer drug

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