Effects of Caesalpinia sappan, sibucao wood decoction on the red blood cell count, hemoglobin concentration and hematocrit of Swiss mice

Date of Publication

1997

Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Biology

College

College of Science

Department/Unit

Biology

Abstract/Summary

A study was conducted to determine the effects of Caesalpinia sappan (sibucao) wood decoction on RBC count, hemoglobin and hematocrit of male Swiss mice. Eighteen male mice were divided into 3 groups with 3 replicates and 3 controls. Treated mice were force-fed with decoction after the initial blood tests. The first group received 1 ml/kg body weight, the second with 1.5 ml/kg body weight and the third with 2 ml/kg body weight of wood decoction. Control mice were force-fed with water. Blood test were conducted at the start of the experiment and every seven days for 2 consecutive weeks of administration of decoction. As the concentration of decoction is increased and as administration is prolonged, the 3 groups of mice significantly increase their RBC count, hemoglobin and hematocrit. The mice group given 2 ml/kg decoction had the greatest increase in RBC count, from 5.5 M/mm to 6.2 M/mm. Hemoglobin content initially was 198.33 g/L and then went up to 231.67 g/L. Hematocrit increased from 53.67 % to 63.33 %.

Abstract Format

html

Language

English

Format

Print

Accession Number

TU07576

Shelf Location

Archives, The Learning Commons, 12F, Henry Sy Sr. Hall

Physical Description

36 numb. leaves

Keywords

Erythrocytes; Mice; Extracts; Trees; Medicinal plants; Hemoglobin; Hematocrit; Blood--Examination; Wood

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