Effects of Atalantia retusa Merr. (Rutaceae) leaves nonpolar extract on the histology of liver, kidney and seminiferous tubule and on sperm count, morphology and other sperm activities in mice

Date of Publication

2009

Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Biology

Subject Categories

Biology

College

College of Science

Department/Unit

Biology

Thesis Adviser

Dennis Raga

Abstract/Summary

The study investigated on the effects of Atalantia retusa leaves nonpolar extract on liver, kidney and seminiferous tubule histology and on sperm count, morphology and other sperm activities in mice. The study made use of the ethyl acetate extract of A. retusa leaves orally administered to male mice for 18 days. The mice were sacrificed at day 19 and sperm count, morphology and sperm activities were noted. There were significant changes on the left epididymal sperm count (P < 0.05), percent viability (P < 0.05), motility, flagellar beat and velocity (P < 0.05) for both left and right cauda epididymis. Toxic effects were observed in the liver, kidney and seminiferous tubule in all doses tested. The results suggest that the nonpolar extract has reproductive and systemic toxicity potentials.

Abstract Format

html

Language

English

Format

Electronic

Accession Number

CDTU019036

Shelf Location

Archives, The Learning Commons, 12F, Henry Sy Sr. Hall

Physical Description

1 computer optical disc ; 4 3/4 in.

Keywords

Rutaceae; Plants--Identification

Embargo Period

12-6-2021

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