GlucoBlock: Preventive Phytomedicine Utilization from Dietary Fibers of Banana (Musa acuminata), Sweet Potato (Ipomoea batatas), and Cassava (Manihot esculenta) for Glucose Regulation via In Vitro Analysis

Proponent/s Name/s (Last Name, First Name, Middle Initial)

• Fiona Angel L. Tubig, University of the CordillerasFollow
• Edgardo N. Dupo III, University of the Cordilleras
• Zynner Joash H. Lingayo, University of the Cordilleras
• Pio Francis Gabriel B. Daet, University of the Cordilleras
• Rain Hart M. Bautista, University of the Cordilleras

Document Types

Paper Presentation

Research Theme (for Paper Presentation and Poster Presentation submissions only)

Food, Nutrition, and Health (FNH)

School Name

University of the Cordilleras

Track or Strand

Science, Technology, Engineering, and Mathematics (STEM)

Research Advisor (Last Name, First Name, Middle Initial)

Diso, Mary Grace, D. & Hipono, Jyka Reego, S.

Start Date

23-6-2026 1:30 PM

End Date

23-6-2026 3:00 PM

Zoom Link/ Room Assignment

DLSU Manila Campus (In-person) - Brother Andrew Gonzalez Multipurpose Hall, 20th floor

Abstract/Executive Summary

The rising prevalence of Type 2 Diabetes Mellitus (T2DM) necessitates accessible and natural preventive strategies. This study evaluated the glucose-regulating potential of dietary fibers from banana (Musa acuminata), sweet potato (Ipomoea batatas), and cassava (Manihot esculenta) peels, and identified the most effective fiber ratio mixtures for regulating glucose absorption, diffusion, and retention within prediabetic ranges (100–125 mg/dL). A completely randomized design was employed using the dialysis tube method to simulate intestinal glucose transport. Ten fiber ratio treatments were compared with Psyllium and No-Fiber controls. Glucose concentrations were measured using a digital glucose refractometer and analyzed through one-way ANOVA and Tukey’s post hoc test. Optimized fiber mixtures reduced glucose levels to the normal range (70–99 mg/dL) without inducing hypoglycemia. Significant differences were observed between the Best Ratio treatments and the No-Fiber control (p < 0.001), while no significant difference was found compared to Psyllium (p > 0.05). These findings indicate that combined soluble and insoluble fibers from agricultural waste provide a cost-effective and sustainable preventive approach to glucose regulation, supporting public health efforts aligned with Sustainable Development Goal 3.

Keywords

dietary fiber; glucose regulation; dialysis tube method; phytomedicine; prediabetes

Initial Consent for Publication

yes

Statement of Originality

yes