Experiment 3: Bromination nd debromination of cholesterol (addition, elimination)

Added Title

Bromination nd debromination of cholesterol (addition, elimination)

College

College of Science

Department/Unit

Chemistry

Document Type

Archival Material/Manuscript

Publication Date

2009

Abstract

The usual methods of synthesizing commercial cholesterol results in contamination with small amounts of cholesterol derivatives mainly 3β-cholesterol, 7-cholesterol-3β-ol, 5,7-cholestadien-3 β-ol and cerebrosterol or 24-hydroxycholesterol 1 . Complete purification of Cholesterol (5-cholesten-3β-ol) was done by bromination reaction producing dibromocholesterol and debromination reaction of dibromocholesterol to produce pure cholesterol. The effectiveness of the experiment was evaluated by melting point determination. Thin Layer Chromatography analysis and through IR analysis. The experiment showed a percentage yield of 67.34 percent on the final product.

html

Disciplines

Chemistry

Keywords

Bromination; Cholesterol—Synthesis

Upload File

wf_no

This document is currently not available here.

Share

COinS