Molecular importance of new roles of retinoids in biological systems: A review
College
College of Science
Department/Unit
Biology
Document Type
Article
Source Title
CvSU Research Journal
Volume
13
Issue
1&2
First Page
74
Last Page
86
Publication Date
1999
Abstract
Retinoids, a group of compounds which include Vitamin A, has recently been shown to play new roles in gene regulation specifically controlling expression of homeotic genes. The implication of this role to developmental process particularly axial patterning, teratogenesis and cancer treatment is discussed. Mechanism for retinoid's molecular action is presented. The occurrence of DNA-binding retinoid receptors (RAR and RXRs) and the identification of several retinoic acid response elements (RAREs) evidenced retinoid' s molecular importance to cell. Updated review on absorption, metabolism, function, deficiency effects and retinoid binding proteins is included.
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Recommended Citation
Heralde, F. M. (1999). Molecular importance of new roles of retinoids in biological systems: A review. CvSU Research Journal, 13 (1&2), 74-86. Retrieved from https://animorepository.dlsu.edu.ph/faculty_research/7381
Disciplines
Biochemistry, Biophysics, and Structural Biology
Keywords
Retinoids
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