Secondary metabolites from cycas edentata

College

College of Science

Department/Unit

Chemistry

Document Type

Article

Source Title

Journal of Pharmaceutical Sciences and Research

Volume

7

Issue

9

First Page

643

Last Page

646

Publication Date

1-1-2015

Abstract

© 2015, Pharmainfo Publications. All rights reserved. Objective: The study was undertaken to isolate the chemical constituents of the dichloromethane extracts of the sarcotesta, endotesta, leaflets and male cone of Cycas edentata. Methods: The compounds were isolated by silica gel chromatography and identified by nuclear magnetic resonance spectroscopy. Results: The dichloromethane extracts of C. edentata afforded β-sitosteryl-3β-glucopyranoside-6'-O-palmitate (1) from the sarcotesta; β-sitosteryl fatty acid ester (2), unsaturated fatty acid methyl esters (3), and a mixture of β-sitosterol (4a) and stigmasterol (4b) in about 5:1 ratio from the endotesta; chlorophyll a (5) from the leaflets; and triacylglycerols (6) from the male cone.The structures of 1‒6 were identified by comparison of their NMR data with those reported in the literature. Conclusion: The different parts of C. edentata yielded as a major constituent β-sitosterol which was also found in other Cycas species. β- Sitosteryl fatty acid ester isolated from the endotesta was also reported from the bark and sclerotesta. Keywords: Cycas edentata, Cycadaceae, β-sitosteryl-3β-glucopyranoside-6'-O-palmitate, β-sitosteryl fatty acid ester, β-sitosterol.

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