Collagen extract from chicken skin as clot actovator
Added Title
Collagen extract from chicken skin as clot activator
College
Ramon V. Del Rosario College of Business
Department/Unit
Management and Organization Department
Document Type
Archival Material/Manuscript
Abstract
This research goals to determine the ability of collagen extracted from chicken skin as a clot activator. It sought to identify the (1) duration of the collagen extract to induce optimum blood clot formation; (2) significant difference between each concentration of the test; and, (3) most effective concentration as an in vitro clot activator. The collagen was extracted bases on Pacak’s improved method for the preparation of type I collagen from skin and then identified by Van Gieson’s stain. This was then tested on 3 patients at 3 different concentrations 1:30, 1:40 and 1:50 in a triplicate manner. Results show that blood treated with collagen at 1:40 has a lower standard deviation (1.92188) from the control and has fastest clotting time (20.2957) among the thee. On the other hand, Tukey’s post hoc test proved that concentrations at 1:40 and 1:50 both showed effectivity. With this, the researchers reject the null hypotheses, concluding that (1) the clot formation takes shorter time than the control; (2) there is a significant difference among the different concentrations thereby, the higher the concentration; and, (3) among all the different volume of blood used, 4mL of blood, has the most potent activity in inducing the clotting activity.
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Recommended Citation
Dizon, M. S., & Balatbat, M. S. (2022). Collagen extract from chicken skin as clot actovator. Retrieved from https://animorepository.dlsu.edu.ph/faculty_research/5995
Disciplines
Hemic and Lymphatic Diseases
Keywords
Collagen; Blood—Coagulation; Chickens
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