Extract from Acanthopanax senticus harms (Siberian ginseng) activates NTS and SON/PVN in the rat brain
College
College of Science
Department/Unit
Biology
Document Type
Article
Source Title
Bioscience, Biotechnology, and Biochemistry
Volume
72
Issue
9
First Page
2476
Last Page
2480
Publication Date
9-2008
Abstract
The extract of the stem bark of Siberian ginseng, Acanthopanax senticosus Harms (ASH), is believed to play a body-coping role in stress through a brain noradrenergic mechanism. The present study was carried out to investigate the effect of ASH on the neuronal activation patterns of c-Fos expression in the rat brain. With ASH administration, c-Fos accumulated in both the supraoptic nuclei (SON) and paraventricular nuclei (PVN), which regulate stress response. Only the caudal regions in the nucleus of the solitary tract (NTS), a locus innervating both the SON and PVN, were activated. Such a neuro-anatomical pattern associated with ASH suggests the possible involvement of these stress-related brain loci.
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Recommended Citation
Soya, H., Deocaris, C. C., Yamaguchi, K., Ohiwa, N., Saito, T., Nishijima, T., Kato, M., Tateoka, M., Matsui, T., Okamoto, M., & Fujikawa, T. (2008). Extract from Acanthopanax senticus harms (Siberian ginseng) activates NTS and SON/PVN in the rat brain. Bioscience, Biotechnology, and Biochemistry, 72 (9), 2476-2480. Retrieved from https://animorepository.dlsu.edu.ph/faculty_research/5465
Disciplines
Biology
Keywords
Acanthopanax senticosus; Brain stimulation; Hypothalamus; Medulla oblongata
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