Lack of antibacterial activity of aqueous and ethanolic leaf extracts of Ziziphus talanai (Blanco) Merr.

Document Type

Article

Source Title

Journal of Pharmaceutical Negative Results

Volume

9

Issue

1

First Page

44

Last Page

48

Publication Date

1-1-2018

Abstract

Objective: The objective of the study is to investigate the phytochemicals and potential antibacterial activity of aqueous and ethanolic leaf extracts of Ziziphus talanai. Materials and Methods: Aqueous and ethanolic crude leaf extracts were subjected to phytochemical screening and assayed for their antimicrobial activities via paper disc diffusion method against Escherichia coli and Staphylococcus aureus. Results: Glycosides, condensed tannins, and saponins were found present in the two extracts; however, leucoanthocyanins were additionally detected in the aqueous extract. Both extracts exhibited no antibacterial activity against E. coli and S. aureus as indicated by the absence of a zone of inhibition. Conclusion: The results of the present study suggest a limited presence of phytochemicals in the crude aqueous and ethanolic leaf extracts of Z. talanai. Water can extract more phytochemicals from Z. talanai leaves than ethanol. However, the results further suggest that the phytochemicals from the leaves extracted using water and ethanol do not have antibacterial activities against E. coli and S. aureus. The negative results of the antimicrobial assay using the crude leaf extracts may not be generalized as lack of bioactivity of the other parts of Z. talanai. © 2018 Journal of Pharmaceutical Negative Results.

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Digitial Object Identifier (DOI)

10.4103/jpnr.JPNR_7_18

Disciplines

Biology

Keywords

Ziziphus--Analysis; Antibacterial agents; Phytochemicals

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