Chemical constituents of Artocarpus camansi

College

College of Science

Department/Unit

Chemistry

Document Type

Article

Source Title

Pharmacognosy Journal

Volume

5

Issue

2

First Page

80

Last Page

82

Publication Date

3-1-2013

Abstract

The dichloromethane extract of the leaves of Artocarpus camansi afforded friedelinol (1), squalene (2), β-sitosterol (3), stigmasterol (4) and phytol (5), while the stems yielded polyprenol (6), cycloartenol (7) and cycloartenol acetate (8). The structures of 1, 7 and 8 were elucidated by extensive 1D and 2D NMR spectroscopy. The cytotoxicity of these triterpenes were tested using the sulforhodamine B assay against the human cancer cell lines: lung adenocarcinoma A549 cells, stomach adenocarcinoma AGS cells, colon adenocarcinoma HT29 cells and prostate cancer PC3 cells. Results of the study indicated that 1, 7 and 8 are non-cytotoxic against these cell lines. Copyright © 2013, Phcog.Net, Published by Reed Elsevier India Pvt. Ltd. All rights reserved.

html

Digitial Object Identifier (DOI)

10.1016/j.phcgj.2012.06.001

Disciplines

Chemistry

Keywords

Artocarpus--Analysis

Upload File

wf_no

This document is currently not available here.

Share

COinS