Chemical constituents of Artocarpus camansi
College
College of Science
Department/Unit
Chemistry
Document Type
Article
Source Title
Pharmacognosy Journal
Volume
5
Issue
2
First Page
80
Last Page
82
Publication Date
3-1-2013
Abstract
The dichloromethane extract of the leaves of Artocarpus camansi afforded friedelinol (1), squalene (2), β-sitosterol (3), stigmasterol (4) and phytol (5), while the stems yielded polyprenol (6), cycloartenol (7) and cycloartenol acetate (8). The structures of 1, 7 and 8 were elucidated by extensive 1D and 2D NMR spectroscopy. The cytotoxicity of these triterpenes were tested using the sulforhodamine B assay against the human cancer cell lines: lung adenocarcinoma A549 cells, stomach adenocarcinoma AGS cells, colon adenocarcinoma HT29 cells and prostate cancer PC3 cells. Results of the study indicated that 1, 7 and 8 are non-cytotoxic against these cell lines. Copyright © 2013, Phcog.Net, Published by Reed Elsevier India Pvt. Ltd. All rights reserved.
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Digitial Object Identifier (DOI)
10.1016/j.phcgj.2012.06.001
Recommended Citation
Tsai, P., De Castro-Cruz, K. A., Shen, C., Chiou, C., & Ragasa, C. Y. (2013). Chemical constituents of Artocarpus camansi. Pharmacognosy Journal, 5 (2), 80-82. https://doi.org/10.1016/j.phcgj.2012.06.001
Disciplines
Chemistry
Keywords
Artocarpus--Analysis
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