Antimicrobial terpenoids from Pterocarpus indicus

College

College of Science

Department/Unit

Chemistry

Document Type

Article

Source Title

Natural Product Research

Volume

19

Issue

4

First Page

305

Last Page

309

Publication Date

6-1-2005

Abstract

A mixture of loliolide 1 (> 85%) and paniculatadiol 2 (< 15%) was obtained from the ethyl acetate leaf extract of Pterocarpus indicus by silica gel chromatography, while the air-dried flowers afforded lupeol 3 and phytol esters 4. The structures of 1-4 were determined by NMR spectroscopy. Antimicrobial tests on a mixture of 1 and 2 indicated that it has moderate activity against Candida albicans and low activity against Pseudomonas aeruginosa, Escherichia coli, and Aspergillus niger. It was found inactive against Staphylococcus aureus, Bacillus subtilis, and Trichophyton mentagrophytes. © 2005 Taylor & Francis Group Ltd.

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Digitial Object Identifier (DOI)

10.1080/14786410410001704822

Disciplines

Chemistry

Keywords

Pterocarpus; Terpenes

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