Bioactive triterpenes from Diospyros blancoi
College
College of Science
Department/Unit
Chemistry
Document Type
Article
Source Title
Natural Product Research
Volume
23
Issue
13
First Page
1252
Last Page
1258
Publication Date
9-1-2009
Abstract
The ethyl acetate extract of the air-dried leaves of Diospyros blancoi afforded isoarborinol methyl ether (1), a mixture of -amyrin palmitate, -amyrin palmitoleate, -amyrin palmitate and -amyrin palmitoleate (2) in a 13 : 4 : 3 : 1 ratio, and squalene. The structures of 1, 2 and squalene were elucidated by extensive 1D and 2D NMR spectroscopy. Compounds 1 and 2 exhibited antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Candida albicans, Staphylococcus aureus and Trichophyton mentagrophytes, and were found inactive against Bacillus subtilis and Aspergillus niger. Sample 2 exhibited significant analgaesic and anti-inflammatory activities.
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Digitial Object Identifier (DOI)
10.1080/14786410902951054
Recommended Citation
Ragasa, C. Y., Puno, M., Sengson, J. P., Shen, C., Rideout, J. A., & Raga, D. D. (2009). Bioactive triterpenes from Diospyros blancoi. Natural Product Research, 23 (13), 1252-1258. https://doi.org/10.1080/14786410902951054
Disciplines
Chemistry
Keywords
Diospyros--Analysis; Amyrin; Analgesics; Anti-inflammatory agents; Anti-infective agents; Ebenaceae
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