Supercritical carbon dioxide-mediated hydrothermal extraction of bioactive compounds from Garcinia Mangostana pericarp

College

Gokongwei College of Engineering

Department/Unit

Chemical Engineering

Document Type

Article

Source Title

Journal of Supercritical Fluids

Volume

110

First Page

167

Last Page

175

Publication Date

4-1-2016

Abstract

Supercritical carbon dioxide in combination with hydrothermal process was used in the extraction of bioactive compounds from Garcinia mangostana pericarp. The extraction was carried out following pre-defined ranges of temperature (120-160 °C), pressure (5-15 MPa), extraction time (30-120 min), and particle size (0.3-0.9 mm), that served as parameters for determination of optimum yield. The extracts were subsequently analyzed for their total polyphenolic contents, antioxidant activity, and alpha-mangostin recovery. The multi-variable extraction process yielded several possible responses. Using response surface methodology (RSM) with central composite design (CCD), the optimal response obtained a yield of 39.9% w/w, with 22.0 gGAE/100 gextract of total polyphenolic contents, together with 73.2 μg/mL of antioxidant activity and 0.203% w/wextract recovery of alpha-mangostin. © 2015 Elsevier B.V. All rights reserved.

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Digitial Object Identifier (DOI)

10.1016/j.supflu.2015.11.016

Disciplines

Chemical Engineering

Keywords

Mangosteen; Bioactive compounds

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