The structure of a novel cembranoid diterpene from a Philippine collection of the soft coral Sinularia flexibilis

College

College of Science

Department/Unit

Chemistry

Document Type

Article

Source Title

Journal of Natural Products

Volume

58

Issue

8

First Page

1185

Last Page

1191

Publication Date

8-1995

Abstract

A new optically active dipertene lactone, sinulariolone [1], has been isolated as the major secondary metabolite in a Philippine collection of Sinularia flexibilis. The compound has a tricyclic structure and is more highly oxygenated than previously reported diterpenes from this species. The structure of 1 was elucidated by spectroscopy, and its relative stereochemistry confirmed by a single-crystal X-ray crystallography

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Disciplines

Chemistry

Keywords

Diterpenes; Alcyonacea—Philippines

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