Synthesis of glucosamine-conjugated metal complexes for anticancer and anti-metastatic targeted therapy

Authors

Laurenzo De Vera Alba
Tsubasa Hatanaka, Osaka University
Misaki Nakai, Kansai University
Shigenobu Yano, Nara Women's University
Yasuhiro Funahashi, Osaka University

College

College of Science

Document Type

Archival Material/Manuscript

Publication Date

2018

Abstract

Platinum and palladium complexes of the Schiff base of glucosamine and 8-hydroxy-2- quinolinecarboxaldehyde (OQN) were synthesized by the reaction of either Pt(DMSO)iCb or Na2PdCl4 in methanol with the ligand. Single crystal X-ray diffraction analysis revealed that these complexes form different dimeric structures with TI-TI stacking and metal-metal interactions in the solid states.

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Recommended Citation

Alba, L. D., Hatanaka, T., Nakai, M., Yano, S., & Funahashi, Y. (2018). Synthesis of glucosamine-conjugated metal complexes for anticancer and anti-metastatic targeted therapy. Retrieved from https://animorepository.dlsu.edu.ph/faculty_research/11264

Disciplines

Chemistry

Keywords

Glucosamine—Synthesis; Metal complexes; Cancer—Treatment

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