Date of Publication

12-5-2025

Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Biochemistry

Subject Categories

Biochemistry

College

College of Science

Department/Unit

Chemistry

Thesis Advisor

Mariafe N. Calingacion
Joan Candice V. Ondevilla

Defense Panel Member

Raymond S. Malabed
Aldrin P. Bonto

Abstract/Summary

The increasing prevalence of e-cigarette use, particularly among Filipino youth, raises significant public health concerns regarding potential exposure to heavy metals from closed-system devices. This study aims to quantitatively analyze the presence of heavy metals in e-cigarette aerosol and assess the associated inhalation risks. Utilizing Inductively Coupled Plasma Mass Spectrometry (ICP-MS), the research detected six heavy metals elements—chromium , copper, iron, manganese, nickel, and lead—in e-cigarette aerosol, with cadmium found to be undetectable. The inhalation exposure assessment revealed that certain metal concentrations exceeded the Recommended Exposure Limits (REL) established by the National Institute for Occupational Safety and Health (NIOSH), raising critical safety concerns for consumers. Additionally, the inhalation cancer risk assessment highlighted significant risks associated with prolonged exposure to chromium and nickel, emphasizing the potential long-term health implications of using closed-system e-cigarettes. The study confirmed that toxic metals leach from the heating elements of e-cigarettes, with significant levels of chromium, nickel, and lead detected in the aerosol. Given these preliminary findings, future research is strongly encouraged to expand the analysis to include additional toxic metals such as arsenic, as well as the incorporation of a larger sample size with multiple brands and flavors. Future researchers are also encouraged to establish a Limit of Detection and Quantification for data reliability, standardization of puffing simulations. and employing speciation analysis.

Abstract Format

html

Language

English

Format

Electronic

Keywords

Electronic cigarettes; Heavy metals; Youth--Philippines; Inductively coupled plasma spectrometry

Upload Full Text

wf_yes

Embargo Period

12-14-2025

Available for download on Sunday, December 14, 2025

Share

COinS