Date of Publication

4-2025

Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Biology major in Molecular Biology and Biotechnology

Subject Categories

Genomics

College

College of Science

Department/Unit

Biology

Thesis Advisor

Priscilla Hope P. Swann

Defense Panel Chair

Jane Abigail S. Santiago

Defense Panel Member

Hilarie P. Orario
Jody M. Benedicto

Abstract (English)

Staphylococcus aureus is a highly infectious pathogen of global importance and is rapidly increasing in developing countries, especially with increased global antibacterial resistance and the emergence of methicillin-resistant Staphylococcus aureus (MRSA) strains. Genomic profiling can aid in determining the priority strains for infection control. This study determined the genomic profile of samples from Southeast Asian countries Vietnam, Thailand, Malaysia, and Philippines in silico using the tools MLST, spaTyper, and SCCmecFinder, available in the Center for Genomic Epidemiology. The MLST, SCCmec, and spa types were determined and ST30-MRSA-SCCmec type IV-spa type t019 and ST239-MRSA-SCCmec type III-spa type t037 were identified as the predominant strains in Southeast Asia. However, few overlaps in the sequence types, SCCmec profiles, and spa types were found between countries.

Abstract Format

html

Abstract (Filipino)

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Abstract Format

html

Language

English

Format

Electronic

Keywords

Staphylococcus aureus--Southeast Asia

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Embargo Period

8-4-2025

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