Date of Publication

7-2025

Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Biology major in Medical Biology

Subject Categories

Medicine and Health Sciences | Oncology

College

College of Science

Department/Unit

Biology

Thesis Advisor

Eligio Santiago V. Maghirang

Defense Panel Chair

Maribel Dominguez

Defense Panel Member

Mark Archei O. Javier
Jandeil B. Roperos

Abstract (English)

Women are more susceptible to endocrine disorders upon reaching the reproductive age. The most prevalent is Polycystic Ovary Syndrome (PCOS). The lifestyle of diagnosed women has declined due to a variety of outcomes such as infertility, metabolic disruptions, and psychological disturbances. The pathophysiology of PCOS reveals the influence of genetic factors and the presence of biomarkers. This systematic review aims to evaluate data on genetic predisposition and biomarkers of PCOS. The data is narrowed to focus on Filipino women, from Metro Manila and Cebu, diagnosed with the disorder. Upon conducting a comprehensive search following the PRISMA 2020 guidelines, only four out of 500 studies were eligible. The results show that the levels of the Anti-Müllerian Hormone (AMH) are consistent between the two populations of Filipino women. Findings suggest that Filipino women with PCOS present with low clinical hyperandrogenism, while metabolic disruptions are more prevalent. Furthermore, this study indicates a significant research gap in PCOS literature in the Philippines.

Abstract Format

html

Abstract (Filipino)

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Abstract Format

html

Language

English

Format

Electronic

Keywords

Polycystic ovary syndrome--Philippines; Physiology, Pathological; Genes; Biochemical markers; Women—Diseases--Philippines

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Embargo Period

8-10-2025

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