Secondary metabolites from Glinus oppositifolius

Date of Publication

12-2012

Document Type

Master's Thesis

Degree Name

Master of Science in Chemistry

Subject Categories

Chemistry

College

College of Science

Department/Unit

Chemistry

Thesis Adviser

Consolacion Y. Ragasa

Defense Panel Chair

Jaime Raul Janairo

Defense Panel Member

Alicia M. Aguinaldo
Glenn V. Alea

Abstract/Summary

The dichloromethane extract of the air-dried stems of Glinus oppositifolius (syn. Mollugo spergula and Mollugo oppositifolia) afforded spergulagenin A and squalene by silica gel chromatography. The structure of spergulagenin A was elucidated by extensive 1D and 2D NMR spectroscopy. This is the first report on the isolation of spergulagenin A from the stems and the first complete 1H and 13C NMR assignments of the compound. Squalene was identified by comparison of its 1H NMR spectral data with those found in the literature. The dichloromethane extract of the air-dried leaves of G. oppositifolius afforded lutein, spinasterol, phytol, squalene, oppositifolone, and oleanolic acid by silica gel chromatography. Lutein, oleanolic acid, and oppositifolone were identified by comparison of their 1H NMR and 13C NMR spectral data with those found in the literature. Spinasterol, phytol, and squalene were identified by comparison of their 1H NMR spectral data with those found in the literature. This is the first reported isolation of phytol from the plant. The air-dried roots of G. oppositifolius afforded spinasterol by silica gel chromatography. Spinasterol was identified by comparison of its 1H NMR spectral data with those found in the literature.

Abstract Format

html

Language

English

Format

Electronic

Accession Number

CDTG005210

Shelf Location

Archives, The Learning Commons, 12F Henry Sy, Sr. Hall

Keywords

Metabolites; Glinus oppositifolius—Analysis

Embargo Period

6-7-2023

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