Date of Publication
1-2000
Document Type
Master's Thesis
Degree Name
Master of Science in Chemistry
Subject Categories
Chemistry
College
College of Science
Department/Unit
Chemistry
Thesis Adviser
Gerardo C. Janairo
Defense Panel Chair
Glenn V. Alea
Defense Panel Member
Eric L. De Leon
Aristea V. Bayquen
Abstract/Summary
Symmetrical dimercaptoisotrithione (DMIT)- and tetrathiafulvalene (TTF)- sugar derivatives attached to C-6 of the sugar moieties were synthesized (7, 8a-b). The synthesis of the DMIT-sugar derivative (7) involved the reaction of bis(tetraethylammonium)bis(1,3-dithiole-2-thione-4,5-dithiolato)zincate(II) with 1,2,3,4-tetra-o-acetyl-6-deoxy-6-iodo-a-d-glucopyranoside in dimethyl formamide. Harsh coupling conditions with thriethyl phosphite [P(OEt)3] gave negative results for the synthesis of symmetrical TTF-sugar derivative (8)a. This problem was circumvented by using tetra(cyanoethylthio)tetrathiafulvalene (TCT-TTF) (4) to generate the tetrathiolate (TTFTT) nucleophile for the synthesis of (8a), followed by its hydrolysis to produce (8b).
1H-, 13C-, 13C-DEPT and HMQC NMR, FTIR and mass spectral data were obtained for structure elucidation.
Abstract Format
html
Language
English
Format
Accession Number
TG07378
Keywords
Tetrathiafulvalene; Sugar—Derivatives
Upload Full Text
wf_yes
Recommended Citation
Galian, R. F. (2000). Novel diMmercaptoisotrithione (DMIT) and tetrathiafulvalene (TTF) with glucose units: Synthesis and characterization. Retrieved from https://animorepository.dlsu.edu.ph/etd_masteral/6293
Embargo Period
9-6-2022
