Date of Publication

2007

Document Type

Master's Thesis

Degree Name

Master of Science in Chemistry

Subject Categories

Chemistry

College

College of Science

Department/Unit

Chemistry

Thesis Adviser

Consolacion Y. Ragasa

Defense Panel Chair

Jaime Raul O. Janairo

Defense Panel Member

Glenn V. Alea
Alicia M. Aguinaldo

Abstract/Summary

Two ornamental plants, Rosa sp.., commonly known as red rose and Allamanda neriifolia Hook., also known as yellow bell were studied for their chemical constituents. The air-dried flowers of Rosa sp. afforded 2- oxopomolic acid by silica gel chromatography. Its structure was elucidated by extensive 1D & 2D NMR spectroscopy. This is the first report on the complete NMR assignments of 2- oxopomolic acid. The 2-oxopomolic acid was tested for antimicrobial activity against seven microorganisms. Results of the study indicated that it was active against the fungi, Candida albicans and Trichophyton mentagrophytes with activity index of 0.3 and 0.2 respectively at a concentration of 30 g. It was also found to be slightly active against the bacteria, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus with activity index of 0.1, 0.2 and 0.1 respectively, at the same concentration. It was inactive against Bacillus subtilis and Asperigillus niger. The air-dried petals of Allamanda neriifolia Hook. afforded a new fatty alcohol cinnamate ester by silica gel chromatography. Its structure was elucidated by extensive 1D and 2D NMR spectroscopy. Mass spectroscopy indicated that this substance is composed of cinnamate and a mixture of saturated and unsaturated fatty alcohols with varying chain lengths.

Abstract Format

html

Language

English

Format

Electronic

Accession Number

CDTG004373

Shelf Location

Archives, The Learning Commons, 12F Henry Sy Sr. Hall

Physical Description

150 leaves ; 28 cm.

Keywords

Metabolites; Roses; Bacillus subtilis

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