Date of Publication

2007

Document Type

Master's Thesis

Degree Name

Master of Science in Chemistry

College

College of Science

Department/Unit

Chemistry

Thesis Adviser

Consolacion Y. Ragasa

Defense Panel Chair

Jaime Raul O. Janairo

Defense Panel Member

Glenn B. Alea
Alicia M. Aguinaldo

Abstract/Summary

Chromolaena odorata (Linn.) King & H. Rob. afforded 5,6,7,4- tetramethoxyflavone (C-14) and 4-hydroxy-5,6,7-trimethoxyflavanone (C-16). The structures of the two flavonoids were elucidated by extensive 1D and 2D NMR spectroscopy. The structure of C-16 was confirmed by comparison of its 1H NMR spectral data with those reported in the literature.

C-14 was tested for antimicrobial potential by the agar well method against seven microorganisms. Results of the study indicated low antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and low antifungal activity against Candida albicans and Trichophyton mentagrophytes. It was found inactive against Bacillus subtilis and Aspergillus niger.

Abstract Format

html

Language

English

Format

Print

Accession Number

TG04227; CDTG004227

Shelf Location

Archives, The Learning Commons, 12F Henry Sy Sr. Hall

Physical Description

xiv, 94 leaves ; 28 cm.

Keywords

Flavonoids; Chromolaena odorata; Dichloromethane

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