Date of Publication

1996

Document Type

Master's Thesis

Degree Name

Master of Science in Chemistry

Subject Categories

Biochemistry, Biophysics, and Structural Biology | Chemistry

College

College of Science

Department/Unit

Chemistry

Thesis Adviser

Gerardo C. Janairo

Defense Panel Chair

Consolacion Y. Ragasa

Defense Panel Member

Marissa G. Noel

Abstract/Summary

The air dried leaves of Lantana camara (family: Verbenaceae, Common name: cononitas) afforded 22 B-Dimethyacryloyloxylantanolic acid, a mixture of 22 B-Dimethyacryloyloxylantanolic acid and 22 B-Angeloyloxylantanolic acid an impure lantanolic and a novel triterpene by gravity column chromatography (dry packing). The structure of the novel compound was elucidated by NMR (1H,13C, DEPT and COSY) FT-IR spectroscopy and mass spectroscopy. The structures of the known triterpenes were determined by comparing their 1H NMR spectral data with those of the novel compound.The two pure compounds were tested for their antimicrobial potential using the paper disc diffusion method. These compounds exhibit high level of antimicrobial properties against Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Pseudomonas aeruginosa, Sacccharomyces cerevisiae, Aspergillus niger and Candida albicans.

Abstract Format

html

Language

English

Format

Electronic

Accession Number

TG03103

Shelf Location

Archives, The Learning Commons, 12F Henry Sy Sr. Hall

Physical Description

iii, 64 leaves 28 cm.

Keywords

Terpenes; Assaying; Microbial sensitivity tests; Extraction (chemistry); Verbenaceae; Lantana

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