Modified procedures for the phytochemical and cytotoxic screening of natural products

Date of Publication

1996

Document Type

Master's Thesis

Degree Name

Master of Science in Teaching Major in Chemistry

Subject Categories

Chemistry

College

Br. Andrew Gonzalez FSC College of Education

Department/Unit

Science Education

Thesis Adviser

Dr. Anamy C. Paano

Defense Panel Chair

Dr. Adelaida Bago

Defense Panel Member

Dr. Bee Ching Ong
Marissa Noel

Abstract/Summary

This study modifies some commonly-used procedures in screening natural products. The published procedures were used as references for the screening of alkaloids, saponins, cardenolides, tannins and polyphenols, cyanogenic glycosides, and flavonoids. The reference procedures used were selected based on their efficiency, simplicity, and availability of chemicals, materials, and equipment. The result of the screening of a set of plant, using both the modified and the reference procedures, revealed that the modified procedures gave comparable results as the reference procedures. In a second batch of screening using the modified procedures, saponins and tannins were detected in taba-tabakuhan, a moss species, tagulinao and elephant's ear.The cytotoxic screening by brine shrimp assay showed that chichirica, oregano, and guava contained cytotoxic components. This was also true with the other plants like moss, taba-tabakuhan, and tagulinao. The moss extract was found to be significantly toxic.

Abstract Format

html

Language

English

Format

Print

Accession Number

TG02539

Shelf Location

Archives, The Learning Commons, 12F Henry Sy Sr. Hall

Physical Description

91 leaves

Keywords

Extracts; Plant cytotaxonomy; Natural products -- Spectra; Plants; Useful; Microbial sensitivity tests; Medicinal plants

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