Date of Publication

12-12-1996

Document Type

Master's Thesis

Degree Name

Master of Science in Chemistry

Subject Categories

Chemistry

College

College of Science

Department/Unit

Chemistry

Thesis Adviser

Consolacion Y. Ragasa

Defense Panel Chair

Gerardo C. Janairo

Defense Panel Member

Jaime Raul O. Janairo
Marissa G. Noel

Abstract/Summary

Hyptis suaveolens afforded suaveolic acid, suaveolol and ursolic acid from the CHCl3 extract. The structures of suaveolic acid and suaveolol were identified by comparison of their 1H nmr spectral data with those found in the literature,11 while the structure of ursolic acid was identified by 1H nmr spectroscopy and FT-IR.Antimicrobial test conducted on suaveolol, suaveolic acid and ursolic acid using the paper disc diffusion method indicated that they are inactive against the bacteria Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Bacillus subtilis. However, it showed zones of inhibition against the fungi Candida albicans at a concentration of 100 ug/ml.Argemone mexicana afforded four interesting secondary metabolites from its CHCl3 extract: norchelerythrine, norsanguinarine, chelamine and sitosterol-B-D-glycoside. The separation was achieved by repeated gravity column chromatography (dry packing) and recrystallization. The structures of the compounds were elucidated by (1H, 13C, COSY) nmr, spectroscopy, and mass spectrometry.

Abstract Format

html

Language

English

Format

Print

Accession Number

TG02530

Shelf Location

Archives, The Learning Commons, 12F Henry Sy Sr. Hall

Physical Description

108 leaves

Keywords

Lamiaceae--Analysis; Terpenes--Spectra; Extracts; Medicinal plants; Plants, Useful

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