Date of Publication
8-1994
Document Type
Master's Thesis
Degree Name
Master of Science in Chemistry
Subject Categories
Chemistry
College
College of Science
Department/Unit
Chemistry
Thesis Adviser
Consolacion Y. Ragasa
Defense Panel Chair
Gerardo C. Janairo
Defense Panel Member
Jaime Raul Janairo
Marissa Noel
Abstract/Summary
Azadirachta indica, A. Juss (Common name: Neem tree) which belongs to the family Meliaceae, is studied for its terpenoid chemistry. One novel tetranortriterpenoid lactone - Isolate N-6 was isolated from Azadirachta indica, A Juss by Vacuum Liquid Chromatography (VLC) and Gravity Column Chromatography (GCC). The structure of Isolate N-6 was elucidated by High Field Nuclear Magnetic Resonance (NMR) analyses such as 1H, 19C, Distortionless Enhancement by Popularization Transfer (DEPT), 1H-1H Correlation Spectroscopy (COSY) and Mass Spectroscopy (MS).Andrographis paniculata, Nees (Common name: Serpentina) which belongs to the family Acanthaceae, was studied for its terpenoid chemistry. One novel diterpene lactone - alcohol derivative of Isolate Z-7 and one known diterpene - diacetylandrographolide, were isolated from Andrographis paniculata, Nees by Vacuum Liquid Chromatography (VLC) and Gravity Column Chromatography (GCC). Their structures were elucidated by High Field Nuclear Magnetic Resonance (NMR) analyses such as 1H, 1BC, 1H- 1H Correlation Spectroscopy (COSY) and Mass Spectroscopy (MS).
Abstract Format
html
Language
English
Format
Accession Number
TG02245
Shelf Location
Archives, The Learning Commons, 12F Henry Sy Sr. Hall
Physical Description
160 leaves
Keywords
Terpenes--Spectra; Meliaceae; Medicinal plants; Solution (Chemistry); Plants--Composition; Extracts
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Recommended Citation
Nacpil, Z. D. (1994). Isolation and structural elucidation of novel terpenes in Azadirachta indica, A. Juss., Andrographis paniculata, Nees and Cosmos caudatus, H.B.K... Retrieved from https://animorepository.dlsu.edu.ph/etd_masteral/1558
