Antimutagenicity potential of isolates from the chloroform extract of Coleus blumei Benth

Date of Publication

1997

Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Chemistry

Subject Categories

Chemistry

College

College of Science

Department/Unit

Chemistry

Thesis Adviser

Dr. Consolacion Y. Ragasa

Defense Panel Chair

Julita Robles

Abstract/Summary

Chloroform extracts of air dried leaves of Coleus blumei Benth were subjected to gravity column chromatography using the gradient elution technique. The fractions were monitored using thin layer chromatography (TLC) and the spots were visualize by spraying with vanillin sulfuric. The fractions were rechromatographed until pure isolates were obtained. These isolates were tested for antimutagenicity potential by the micronucleus test. Results indicate significant decreases in MPCE for three of the isolates, yielding percent reductions ranging from 20.8% t0 56.6%.

Abstract Format

html

Language

English

Format

Print

Accession Number

TU17468

Shelf Location

Archives, The Learning Commons, 12F, Henry Sy Sr. Hall

Physical Description

30, [11] leaves: illustrations (some colored); 28 cm.

Keywords

Chloroform; Antimutagens

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