Protective effects of vitamin C and E supplementation against alcoholic fatty liver in Mus musculus (Albino mice)

Date of Publication

2010

Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Biology

Subject Categories

Animal Sciences | Biology

College

College of Science

Department/Unit

Biology

Thesis Adviser

Noel Alfonso

Defense Panel Member

Dennis Raga
Jordan De La Rosa
Cindy Lopez

Abstract/Summary

Alcohol consumption has many harmful effects in body especially in the liver. Vitamins, on the other hand, are known to have essential roles in maintaining certain organs. In this study, the protective effect of vitamins C and E against fatty liver induced by excessive alcohol consumption was investigated. Thirty six male albino mice (Mus musculus) were divided into four groups (control, alcohol control, vitamin control and vitamins C and E plus alcohol). Moderate and severely steatotic cells were significantly higher among the alcohol control group compared to the other groups. On the other hand, the control, the vitamin control and the vitamins C and E plus alcohol administered groups mostly showed normal and mildly steatotic liver cells. This shows that vitamins C and E plus alcohol administered groups had lower risks in having steatotic cells compared to that of the alcohol control group. Because of this, vitamins C and E did have a protective effect against alcohol induced mice fatty liver.

Abstract Format

html

Language

English

Format

Electronic

Accession Number

CDTU019214

Shelf Location

Archives, The Learning Commons, 12F, Henry Sy Sr. Hall

Physical Description

1 computer disc ; 4 3/4 in.

Keywords

Vitamin C--Therapeutic use; Vitamin E; Fatty liver--Prevention

Embargo Period

4-29-2021

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