Characterization of malunggay (Moringa oleifera L.) glucosinolates
College of Science
Glucosinolate and their corresponding hydrolytic products have been found to exhibit chemopreventive properties. Malunggay (Moringa oleifera L.) was found to contain a predominant glucosinolate - glucomoringin. In this study, methanol extracts will be prepared from freeze-dried samples of raw and boiled malunggay leaves and seeds which will be immediately followed by desulfation using DEAE Sephadex A-25 resin. The desulfated glucosinolate content of the vegetable samples will be analyzed and compared using HPLC, GC and LC-MS. Powdered samples of raw and boiled malunggay will be defatted using n-hexane and will be allowed to undergo hydrolysis with and without the presence of myrosinase. Air-dried samples will be extracted with DCM and will be subjected to GC-MS and GC-FID analyses. Malunggay juice, powdered samples and DCM extracts will also be subjected to Comet assay to determine whether the samples have potent anti-cancer activities.
Malabed, R. S. (2010). Characterization of malunggay (Moringa oleifera L.) glucosinolates. Retrieved from https://animorepository.dlsu.edu.ph/faculty_research/7983
Glycosides; Moringa oleifera—Analysis