Title

Structure elucidation of β-stigmasterol and β-sitosterol from Sesbania grandiflora (Linn.) pers. and β-carotene from Heliotropium indicum Linn. by NMR spectroscopy

College

College of Science

Department/Unit

Chemistry

Document Type

Article

Source Title

Kimika

Volume

20

Issue

1/2

First Page

5

Last Page

12

Publication Date

2004

Abstract

The flowers of Sesbania grandiflora (Linn.) Pers. afforded a 3:2 mixture of β-stigmasterol (1a) and β-sitosterol (1b), and oleanolic acid (2), while the leaves of Heliotropium indicum Linn. yielded β-carotene (3), lutein ( 4), a mixture of polyprenols (5), and a mixture of β-stigmasterol and β-sitosterol. The structures of 1a, 1b, and 3 were elucidated by extensive 1D and 2D NMR analyses. Antimicrobial activity tests on 3 indicated that it has high activity against Pseudomonas aeruginosa and Aspergillus niger, slight activity against Staphylococcus aureus, Escherichia coli, Candida albicans, and Trichophyton mentagrophytes, and inactive against Bacillus subtilis.

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Disciplines

Chemistry

Keywords

Sesbania—Analysis; Heliotropium—Analysis; Anti-infective agents

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