Structure elucidation of β-stigmasterol and β-sitosterol from Sesbania grandiflora (Linn.) pers. and β-carotene from Heliotropium indicum Linn. by NMR spectroscopy
College of Science
The flowers of Sesbania grandiflora (Linn.) Pers. afforded a 3:2 mixture of β-stigmasterol (1a) and β-sitosterol (1b), and oleanolic acid (2), while the leaves of Heliotropium indicum Linn. yielded β-carotene (3), lutein ( 4), a mixture of polyprenols (5), and a mixture of β-stigmasterol and β-sitosterol. The structures of 1a, 1b, and 3 were elucidated by extensive 1D and 2D NMR analyses. Antimicrobial activity tests on 3 indicated that it has high activity against Pseudomonas aeruginosa and Aspergillus niger, slight activity against Staphylococcus aureus, Escherichia coli, Candida albicans, and Trichophyton mentagrophytes, and inactive against Bacillus subtilis.
Cayme, J. C., & Ragasa, C. Y. (2004). Structure elucidation of β-stigmasterol and β-sitosterol from Sesbania grandiflora (Linn.) pers. and β-carotene from Heliotropium indicum Linn. by NMR spectroscopy. Kimika, 20 (1/2), 5-12. Retrieved from https://animorepository.dlsu.edu.ph/faculty_research/5726
Sesbania—Analysis; Heliotropium—Analysis; Anti-infective agents