Novel β-galactosynthase-β-mannosynthase dual activity of β-galactosidase from: Aspergillus oryzae uncovered using monomer sugar substrates
College of Science
A novel β-galactosynthase-β-mannosynthase dual-activity of β-galactosidase from Aspergillus oryzae was uncovered, for the first time, using free monosaccharide substrates. The enzyme successfully converted galactose and mannose monomer sugars efficiently into Gal-β(1-6)-Gal and Man-β(1-6)-Man, respectively. The discovery could potentially revolutionize chemoenzymatic glycan and non-digestible oligosaccharide (NDO) syntheses. © 2016 The Royal Society of Chemistry.
Digitial Object Identifier (DOI)
Tan, R. S., Hinou, H., & Nishimura, S. I. (2016). Novel β-galactosynthase-β-mannosynthase dual activity of β-galactosidase from: Aspergillus oryzae uncovered using monomer sugar substrates. RSC Advances, 6 (56), 50833-50836. https://doi.org/10.1039/c6ra08060j
Aspergillus; Galactose; Mannose; Monomers