Title

Immunohistochemical detection of S100 in the kidney of the Philippine swamp buffalo (Bubalus bubalis carabanensis Castillo, 1998) (Artiodactyla: Bovidae)

College

College of Science

Department/Unit

Biology

Document Type

Article

Source Title

Philippine Journal of Veterinary Medicine

Volume

52

Issue

2

First Page

65

Last Page

70

Publication Date

1-1-2015

Abstract

The presence of S100 protein in the kidney of Philippine swamp buffalo (Bubalus bubalis carabanensis) was detected using immunohistochemistry. The Avidin-Biotin Peroxidase complex method was carried out with a polyclonal antibody against S100 protein. S100 immunoreactivity was present in the thin loop of Henle, collecting ducts and tubules. Positive immunoreaction was also detected in erythrocytes and endothelial lining cells of arcuate artery and vein, interlobular artery and vein, venules, glomerular and peritubular capillaries. This is the first report of the detection and distribution of S100 protein in the swamp buffalo kidney. This study confirms that S100 can be found extraneurally and can be a useful marker for anatomic pathology.

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Disciplines

Biology

Keywords

Water buffalo--Philippines; Immunohistochemistry; Kidneys; Proteins

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