Chemical constituents of andrographis paniculata (Burm.f.) nees
College of Science
International Journal of Pharmacognosy and Phytochemical Research
Chemical investigation of the dichloromethane extracts of Andrographis paniculata (Burm.f.) Nees led to the isolation of andrographolide (1), 14-deoxyandrographolide (2), 14-deoxy-12-hydroxyandrographolide (3), a mixture of β-sitosterol (4a) and stigmasterol (4b) in a 3:1 ratio, and chlorophyll a (5) from the leaves; a mixture of 4a and 4b in a 3:2 ratio, 5,2'-dihydroxy-7,8-dimethoxyflavone or skullcapflavone I (6), and a mixture of long chain trans-cinnamate esters (7a) and β-sitosteryl fatty acid esters (7b) from the roots; 4a, monogalactosyl diacylglycerols (8), lupeol (9), and triacylglycerols (10) from the pods; and 2 from the stems. The structures of 1-3 and 6 were elucidated by extensive 1D and 2D NMR spectroscopy, while the structures of 4, 5 and 7-10 were identified by comparison of their NMR data with those reported in the literature. © 2016, International Journal of Pharmacognosy and Phytochemical Research. All right reserved.
Tan, M. S., Oyong, G. G., Shen, C., & Ragasa, C. Y. (2016). Chemical constituents of andrographis paniculata (Burm.f.) nees. International Journal of Pharmacognosy and Phytochemical Research, 8 (8), 1398-1402. Retrieved from https://animorepository.dlsu.edu.ph/faculty_research/1160