Title

Chemical constituents of andrographis paniculata (Burm.f.) nees

College

College of Science

Department/Unit

Chemistry

Document Type

Article

Source Title

International Journal of Pharmacognosy and Phytochemical Research

Volume

8

Issue

8

First Page

1398

Last Page

1402

Publication Date

8-1-2016

Abstract

Chemical investigation of the dichloromethane extracts of Andrographis paniculata (Burm.f.) Nees led to the isolation of andrographolide (1), 14-deoxyandrographolide (2), 14-deoxy-12-hydroxyandrographolide (3), a mixture of β-sitosterol (4a) and stigmasterol (4b) in a 3:1 ratio, and chlorophyll a (5) from the leaves; a mixture of 4a and 4b in a 3:2 ratio, 5,2'-dihydroxy-7,8-dimethoxyflavone or skullcapflavone I (6), and a mixture of long chain trans-cinnamate esters (7a) and β-sitosteryl fatty acid esters (7b) from the roots; 4a, monogalactosyl diacylglycerols (8), lupeol (9), and triacylglycerols (10) from the pods; and 2 from the stems. The structures of 1-3 and 6 were elucidated by extensive 1D and 2D NMR spectroscopy, while the structures of 4, 5 and 7-10 were identified by comparison of their NMR data with those reported in the literature. © 2016, International Journal of Pharmacognosy and Phytochemical Research. All right reserved.

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Disciplines

Chemistry

Keywords

Acanthaceae--Analysis

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