Date of Publication

2-2025

Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Biology major in Medical Biology

Subject Categories

Biology

College

College of Science

Department/Unit

Biology

Thesis Advisor

Michael B. Ples

Defense Panel Chair

Michael B. Ples

Defense Panel Member

Marigold O. Uba
Patricio Elvin L. Cantiller
Christian Jordan O. Dela Rosa

Abstract/Summary

Diabetes mellitus is a widespread chronic metabolic disease that is characterized by elevated blood glucose levels. While treatment is primarily done through the use of pharmaceutical drugs, there is a growing interest in investigating natural alternatives, especially with regard to medicinal plants. The study investigated the hypoglycemic potential of mung beans (Vigna radiata), which is a member of the plant family Fabaceae. Members of this plant family are known for their bioactive substances, such as dietary fibers, polyphenols, and peptides. Peer-reviewed studies published between 2019 and 2025 were compiled and synthesized by the researchers. This synthesis consists of five studies that involve the use of various animal models of diabetes. The results revealed that mung bean extracts, which include methanolic, peptide, hydroethanolic, and seed coat formulations, were able to significantly lower fasting blood glucose (FBG) levels. Enhanced insulin sensitivity, pancreatic β-cell regeneration, and modulation of gut microbiota were among the identified mechanisms that contributed to its hypoglycemic capabilities. It was determined, however, that further clinical trials in humans were needed in order to validate these results as well as to be able to explore their long-term efficacy and safety.

Keywords: Vigna radiata, mung beans, hypoglycemia, diabetes mellitus, fasting blood glucose, Fabaceae

Abstract Format

html

Language

English

Format

Electronic

Keywords

Mung bean—Therapeutic use; Hypoglycemia; Diabetes; Legumes; Blood glucose

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Embargo Period

4-14-2025

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