Date of Publication


Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Biology major in Medical Biology

Subject Categories

Biology | Other Medical Sciences


College of Science



Thesis Advisor

Mary Jane C. Flores

Defense Panel Chair

Bridget Co-Arellano

Defense Panel Member

Jessica Joyce de Guia
Frumencio F. Co


A meta-analysis was performed to assess the physiologic effects of helminth infection and investigate its influence on academic performance to identify control initiatives that could improve the health of school children. This study was conducted using Review Manager 5.4 to examine the impact of infection on nutritional and anemic status and cognitive performance to develop an emphasis on a multi-faceted control strategy for implementation in the Philippines. Researchers evaluated 67 journal articles from electronic databases. The included studies were subjected to a publication bias assessment and meta-analysis using a data management software. Outcomes were presented in a forest plot to summarize the findings. Results from the meta-analyses performed for physiological effects showed that none of the three parasites (Ascaris lumbricoides, Trichuris Trichiura, and hookworms) were significantly associated with the risk of malnutrition and that only hookworms were found to be significantly associated with the risk of anemia. The meta-analyses performed for cognitive function found that only the domains of memory under infected and uninfected groups and reaction time under treatment and placebo groups showed significant association between infection and poor cognitive performance. The results suggest that the detrimental effects of parasitic infection require a greater understanding of its physiologic and cognitive features due to its complexity. Anthelmintic treatment is not sufficient to alleviate the burdens of disease and must be supplemented with initiatives that allow social mobility, health education and sanitation development.

Keywords: Trichuris, Ascaris, hookworm, malnutrition, anemia, memory, learning, reaction time, cognition, school children, academic performance

Abstract Format






Physical Description

82 leaves


Whipworms; Ascaris; Hookworms; Malnutrition in children; Helminthiasis; School children—Health and hygiene; Academic achievement

Upload Full Text


2021_Blanquera_Tiffany_Soberano_Katherina_PreliminaryPages.pdf (81 kB)
Preliminary Pages (Title Page, Acknowledgments, Abstract, Table of Contents)

2021_Blanquera_Tiffany_Soberano_Katherina_Chapter1.pdf (77 kB)
Chapter 1: Introduction

2021_Blanquera_Tiffany_Soberano_Katherina_Chapter2.pdf (430 kB)
Chapter 2: Review of Related Literature

2021_Blanquera_Tiffany_Soberano_Katherina_Chapter3.pdf (127 kB)
Chapter 3: Materials and Methods

2021_Blanquera_Tiffany_Soberano_Katherina_Chapter4.pdf (756 kB)
Chapter 4: Results and Discussion

2021_Blanquera_Tiffany_Soberano_Katherina_Chapter5.pdf (13 kB)
Chapter 5: Summary, Conclusion, and Recommendations

2021_Blanquera_Tiffany_Soberano_Katherina_LiteratureCited.pdf (141 kB)
Literature Cited

Embargo Period