Title

Chemical constituents of garcinia benthami pierre

Date of Publication

2018

Document Type

Master's Thesis

Degree Name

Master of Science in Chemistry

College

College of Science

Department/Unit

Chemistry

Thesis Adviser

Consolacion Y. Ragasa

Defense Panel Chair

Jaime Raul O. Janairo
Alicia Aguinaldo

Defense Panel Member

Glenn V. Alea

Abstract/Summary

Garcinia benthami Pierre (syn Garcinia ferrea Pierre) is also known as Bunog by the Cuyunin tribe and Tagbanua in Palawan Philippines. The compounds present in the dichloromethane (DCM) extract of roots, fruit peels, fruit seeds, fruit fleshes, stem barks, leaves and flowers were isolated by using normal phase chromatography and identified by NMR spectroscopic technique. Triacylglycerol (TAG) was isolated in extract of roots, stem barks, flesh and seed of the fruits. Squalene was isolated from roots, fruit peels, stem barks and fruit fleshes extract. Caryophyllene (CAR) was isolated from fruit peels and leaves extract. Methyl (24E)-3 {u1D6FC} ,9 {u1D6FC}, 23-trihydroxy-17,14-friedolanosta-14,24-dien-26-oate was isolated from fruit peels, leaves and flowers extract. While the mixture of {u1D6FD}-sitosterol and stigmasterol was obtained from flowers and fruit seeds extract. Chlorophyll a and {u1D6FC} carotene were only isolated from the leaves and friedelin was only isolated from stem barks extract. A new triterpene (24E)-23 acetoxy-3{u1D6FC}-hydroxylanostane-9(11), 16, 24-trien-26- oic acid were isolated from the roots extract and obtained as part of the mixture with (22Z, 24E)-9 {u1D6FC} -hydroxy-3-oxo-17,14-friedolanosta-14,22-24-trien-26-oic acid and a new triterpene (24E)-9 {u1D6FC}-hydroxy-3-oxo-17,14-friedolanosta-14, 24-dien-26-oic acid from the fruit peels extract. Another mixture of triterpenes, (22Z, 24E)-9{u1D6FC}-hydroxy-3-oxo-17,14- friedolanosta-14,22-24-trien-26-oic acid and Methyl (24E)-9,23-dihydroxy-3-oxo-17,14- friedolanostan-14,24-dien-26-oate (another new triterpene) was obtained from the stem barks.

Abstract Format

html

Language

English

Format

Electronic

Accession Number

CDTG007634

Shelf Location

Archives, The Learning Commons, 12F Henry Sy Sr. Hall

Physical Description

xxiv, 326 pages ; 30 cm. ; 1 computer optical disc ; 4 3/4 in.

Keywords

Dichloromethane; Medicinal plants

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