Title

Triterpenoids from Pouteria campechiana (H.B.K.) Baehni

Date of Publication

2007

Document Type

Master's Thesis

Degree Name

Master of Science in Chemistry

Subject Categories

Chemistry

College

College of Science

Department/Unit

Chemistry

Thesis Adviser

Consolacion Y. Ragasa

Defense Panel Chair

Jaime Raul O. Janairo

Defense Panel Member

Glenn V. Alea
Alicia M. Aguinaldo

Abstract/Summary

The ethyl acetate extract of the stem bark of Pouteria campechiana (H.B.K.) Baehni afforded spinasterol (PC19) and three fatty acid esters of triterpenes: erythrodiol (PC3), betulinic acid (major compound of PC11) and oleanolic acid (minor compound of PC11). The last two were obtained as a mixture (3:1). The structures of PC3 and PC11 were elucidated through extensive 1-D and 2-D NMR analyses. On the other hand, PC19 was identified through a comparison of its 1H NMR spectral data with the one found in the literature. Antimicrobial test results indicated that PC3 has a low activity against Escherichia coli, Candida albicans, Trichophyton mentagrophytes, Pseudomonas aeruginosa and Staphylococcus aureus. It was found to be inactive against Bacillus subtilis and Aspergillus niger. On the other hand, PC11 has a low activity against Escherichia coli, Pseudomonas aeruginosa, Candida albicans and Trichophyton mentagrophytes. It was inactive against Staphylococcus aureus, Bacillus subtilis and Aspergillus niger.

Abstract Format

html

Language

English

Format

Electronic

Accession Number

CDTG004279

Shelf Location

Archives, The Learning Commons, 12F Henry Sy Sr. Hall

Physical Description

xviii, 292 leaves ; 28 cm.

Keywords

Pouteria campechiana; Fruit threes

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